The first conference of the European Research Network on Signal Transduction (ERNEST, COST Action CA18133) will take place at the Queen's University Belfast in Northern Ireland on October 28-30, 2019.
The conference will focus on recent advances in GPCRs pharmacology as well as systems biology strategies for advancing the main goal of ERNEST, namely development of a multidimensional holistic map of GPCR signal transduction. The program will cover GPCR macromolecular interactions in signalling pathways, biological roles of signal transduction and chemical modulators of GPCR signalling. In addition, the meeting will gather technical and conceptual developments in structural determination, functional analysis and computational modelling of GPCR macromolecular complexes. The goal of the meeting is to further our understanding of GPCR signal transduction at the molecular, cellular, and systems level, so as to facilitate the development of more effective GPCRs medicines.
ERNEST brings together an enthusiastic and diverse group of signal transduction researchers in Europe. This first meeting promises not only excellent science, but a unique opportunity to network and build fruitful collaborations across international borders. A special focus will be the training, mentoring and networking of Early Career Investigators (doctoral students and postdocs), who represent the future of the field.
ERNEST consists of five working groups, focusing on different aspects of GPCRs:
Working Group 1: Macromolecular interactions in signalling pathways
Working Group 2: Biological roles of signal transduction
Working Group 3: Molecular modulators of signal transduction
Working Group 4: Advanced methodologies and technologies
Working Group 5: Public web resources
Talks on the themes will be presented during the conference and will provide a platform for communicating the most current scientific progress in GPCRs research.
Dr Irina Tikhonova (Queen’s University Belfast)
Prof Andrew Tobin (University of Glasgow)
Dr Peter McCormick (Queen Mary University of London)